JVIR twitter

Friday, April 3, 2015

Bariatric Embolization for the Treatment of Obesity: A Review

Bariatric embolization has been discussed as a possible treatment for obesity since first early pre-clinical studies were done by Arepally et al in 2007. While much work in this field has been done, there remain many challenges prior to full clinical implementation. The current state of BAE was recently reviewed in JVIR by researchers from Johns Hopkins. Weiss et al. provide a thorough review of the physiologic and anatomic basis along with a review of the preclinical and clinical data. If successful, BAE will represent a minimally invasive solution to obesity offered by interventional radiologists.


Comment:
This manuscript does an excellent job reviewing the topic of BAE. The physiologic and anatomic basis for the procedure along with the current preclinical and clinical data are reviewed well. Clearly there are many challenges to mainstream implementation of this procedure. Many questions remain unanswered. What is the ideal embolic agent? What is the long-term outcome and will this procedure result in sustained weight loss? What is the best method of targeting the appropriate vascular bed? As more robust clinical trials provide answers to these questions, we will be closer to understanding the role this procedure may have in the treatment of this prevalent disease process.


Click here to see the full abstract




Angiogram of the left gastric artery. Fundal (solid arrows) and esophageal (dashed arrow) branches are identified. This LGA shows a large anastomosis (arrowheads) with the right gastric artery along the lesser curvature.


Hormonal changes during the fasting versus fed states. Several hormones are released from the GI tract. The “hunger hormone” ghrelin is secreted from X/A cells in the gastric fundus, whereas PYY and GLP-1 are secreted from L cells, primarily from the ileum and colon. Leptin is primarily produced in adipocytes. During fasting, decreased food intake suppresses the release of PYY, GLP-1, and CCK from the gut while stimulating the secretion of ghrelin by the stomach. Fasting also decreases serum leptin levels. These changes are detected by the brain, leading to hunger. Dieting results in a gut hormone profile that mimics the fasted state. During and after regular feeding, there is a reduction in the production of ghrelin by the stomach. In contrast, production of PYY, GLP-1, and CCK from the gut is increased, and serum leptin levels also increase. These changes, which are detected by the brain, result in decreased appetite and a feeling of satiety.


Citation: Weiss, C. R. et al. Bariatric Embolization of the Gastric Arteries for the Treatment of Obesity. Journal of Vascular and Interventional Radiology (2015). doi:10.1016/j.jvir.2015.01.017


Post author: Luke Wilkins, MD


16 comments:

  1. I was diagnose with genital warts since 2012 i have be taking lot treatment and all i got is outbreak. in 2015 I gave up the treatment because I can't continues wasting time and money on treatment at the end it will not cure me. about 6 weeks ago i did natural research online I had So many people talking good about natural remedy, after the research i was recommended to Dr onokun, And I wrote to him through his email and told him my problem after some conversations with him he gave me natural treatment after 1 week Dr onokun treated me i got cured permanently. and i went to see my doc he confirmed that the diseases has gone out from my body. every patients should know there is 100% natural hpv cure. contact Dr onokun his email address: dronokunherbalcure@gmail.com

    ReplyDelete
    Replies
    1. Just wanna say a big thank you patrice cythia for introducing me to Dr Ezomo the great HERBALIST that helped me prepare home remedies that cured my herpes simplex virus (HSV1&2) I was infected with herpes for the past two years and i was not happy all day so i was desperate to get a cure so that i can live normal and get healthy. One day i was less busy so i decided to make latest research on herpes cure and i found a site were everyone was talking about Dr Ezomo and has ability to cure Herpes, HIV, HPV, Cancer, ALS, COPD, Anthrax, genital wart, cold sore, Arthritis skin tag and all manners of diseases and virus. So i discussed with cythia and she explained to me that its very easy working with Dr Ezomo so i contacted Dr Ezomo via email dr.dr.ezomorootandherbals@gmail.com and he helped me just as he has helped others now I am now cured from herpes am very happy now. and i can also assure you that he can also help you. so if you need the service of DR Ezomo kindly contact him dr.ezomorootandherbals@gmail.com. or whatsapp +2349069171173.He can also cure so many sickness

      Delete
  2. The greatest Joy in my life today is that i have been cured of HIV/AIDS by a Doctor called Dr. Aire,
    Dr. Aire help me in my life. I was infected with HIV/AIDS DISEASE in 2012, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution,so that my body can be okay.until this faithful day as i was browsing the net I saw a testimony on how Dr.Aire helped people in curing HIV disease, quickly I copied his WhatsApp number so i contacted him for solution for my HIV DISEASE,so Dr. Aire told me that his going to prepare herbal medicine for my health,then he prepared the medicine and luckily after 2week my HIV was cured. Dr.Aire is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr. Aire herbal medicine,he also cure HPV,CANCER,HERPES,ALS,HEPATITIS B, DIABETES, ASTHMA,contact him on his email (drairehome@gmail.com) or contact him on WhatsApp via number:+2347036740271

    ReplyDelete
  3. The greatest Joy in my life today is that i have been cured of HIV/AIDS by a Doctor called Dr. Aire,
    Dr. Aire help me in my life. I was infected with HIV/AIDS DISEASE in 2012, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution,so that my body can be okay.until this faithful day as i was browsing the net I saw a testimony on how Dr.Aire helped people in curing HIV disease, quickly I copied his WhatsApp number so i contacted him for solution for my HIV DISEASE,so Dr. Aire told me that his going to prepare herbal medicine for my health,then he prepared the medicine and luckily after 2week my HIV was cured. Dr.Aire is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr. Aire herbal medicine,he also cure HPV,CANCER,HERPES,ALS,HEPATITIS B, DIABETES, ASTHMA,contact him on his email (drairehome@gmail.com) or contact him on WhatsApp via number:+2347036740271

    ReplyDelete
  4. The greatest Joy in my life today is that i have been cured of HIV/AIDS by a Doctor called Dr. Aire,
    Dr. Aire help me in my life. I was infected with HIV/AIDS DISEASE in 2012, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution,so that my body can be okay.until this faithful day as i was browsing the net I saw a testimony on how Dr.Aire helped people in curing HIV disease, quickly I copied his WhatsApp number so i contacted him for solution for my HIV DISEASE,so Dr. Aire told me that his going to prepare herbal medicine for my health,then he prepared the medicine and luckily after 2week my HIV was cured. Dr.Aire is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr. Aire herbal medicine,he also cure HPV,CANCER,HERPES,ALS,HEPATITIS B, DIABETES, ASTHMA,contact him on his email (drairehome@gmail.com) or contact him on WhatsApp via number:+2347036740271

    ReplyDelete
  5. I am John Danilla from UK( northern ireland), i want to share a
    testimony on how a powerful spell caster cured my HIV disease, i was
    diagnosed of this disease, in the year 2009, last week i saw a testimony on
    Dr.Akioya on how he cured an HIV patient, so i contacted him through phone
    and he asked me to email him, which idid, so he told me that all my
    problems is over and then he decided to do an healing spell spell for me so
    after he finished it, he told me to wait for just 24 hours and then i
    should go for a test, so i really did as he had said, so my greatest
    surprised when i went to the hospital to go for an HIV test, the Medical
    doctor diagnosed that, i am now HIV negetative at first i was amazed and
    now i have come to realise that this spell caster Dr. Akioya is a very
    powerful one and a real spell caster. So viewers of this should please join
    me in my celebration for i am the happiest man on earth today and if you
    want to contact him, you can do this via his email
    (drakioya17spellhome@gmail.com or call him or whatsapp him
    +2348105257464. or you can visit is website;
    http://drakioyaherbalcenter.home.blog
    https://drakioyaherbalhome.blogspot.com/

    ReplyDelete
  6. HELLO EVERYONE.. FEW MUNINETS TO REDY THIS INFOR ON HERPES CURE 2018..
    2017 MY MOTHER WAS DIAGNOSED OF HERPES/ KNOWN AS GENITAL WARTS ,I SPENT A LOT OF MONEY ON HER MEDICATION TILL A POINT I EVEN LOST HOPE,BECAUSE MY MOTHER WAS GRADUALLY DYING AND LOST HER MEMORY TOO, I WAS SO DESPERATE TO GET MY MOTHER BACK TO NORMAL, ONE DAY MY UNCLE WHO LIVES IN LONDON UNITED KINGDOM TOLD ME ABOUT DR OLIHA ,WHO HELPED HIM GET RID OF HERPES /GENITAL WART WITH HERBAL MEDICINE AND HIS HERBAL SOAP ,I WAS SO SHOCKED WHEN HE TOLD ME ABOUT THIS ,ALTHOUGH I NEVER BELIEVE IN HERB BUT, I KEEP TO BELIEVE BECAUSE MY UNCLE CAN'T TELL ME LIES WHEN IT COMES TO HEALTH CONDITION I CONTACTED DR OLIHA VIA HIS EMAIL; OLIHA.MIRACLEMEDICINE@GMAIL.COM , YOU CAN TALK TO HIM VIA CALL OR WHATSAPP MESSENGER ON +2349038382931 , HE REPLIED AND ASK ME TO SEND MY HOME ADDRESS AND MY MOTHER'S DETAIL AND THEN I PURCHASED THE HERBAL MEDICINE,SENT ME THE HERBAL MEDICINE THROUGH COURIER SERVICE, WHEN I RECEIVED THIS HERBAL MEDICINE USED IT FOR 2 WEEKS, AND 4 DAYS OF USAGE THE WARTS FELL OFF, MY MOTHER I NOW TOTALLY CURED AND MY MOTHER IS LIVING FREE AND HAPPY AGAIN. YOU CAN TALK TO DR VIA HIS MOBILE NUMBER OR WHATS APP HIM ON +2349038382931.ALL THANKS TO DOCTOR DR OLIHA

    ReplyDelete
  7. Just wanna say a big thank you patrice cythia for introducing me to Dr Ezomo the great HERBALIST that helped me prepare home remedies that cured my herpes simplex virus (HSV1&2) I was infected with herpes for the past two years and i was not happy all day so i was desperate to get a cure so that i can live normal and get healthy. One day i was less busy so i decided to make latest research on herpes cure and i found a site were everyone was talking about Dr Ezomo and has ability to cure Herpes, HIV, HPV, Cancer, ALS, COPD, Anthrax, genital wart, cold sore, Arthritis skin tag and all manners of diseases and virus. So i discussed with cythia and she explained to me that its very easy working with Dr Ezomo so i contacted Dr Ezomo via email dr.dr.ezomorootandherbals@gmail.com and he helped me just as he has helped others now I am now cured from herpes am very happy now. and i can also assure you that he can also help you. so if you need the service of DR Ezomo kindly contact him dr.ezomorootandherbals@gmail.com. or whatsapp +2349069171173.He can also cure so many sickness

    ReplyDelete
  8. I want to share a testimony of how Dr UDI herbal mixture cream saved me from shame and disgrace, my penis was a big problem to me as the size was really so embarrassing ,and i was also having weak erection problem i had so many relationship called off because of my situation, i have used so many product which i found online but none could offer me the help i searched for Which was very painful and then i saw some few testimonies about this herbal specialist called Dr UDI and decided to email him on so I gave his herbal product a try. i emailed him and he got back to me and we discussed, he gave me some comforting words and encouraged me also ans then gave me his herbal pills and cream for Penis Enlargement Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 10 inches longer and am so happy contact Dr UDI via (drudiherbalhome@gmail.com) Via whatapp on this number +2348051243538 or you visit his website
    https://drudiblogaddress.blogspot.com/
    https://drudiherba.home.blog:

    ReplyDelete
  9. I found out, that taking herbal treatment is the best to get rid of (HPV) as soon as i feel the symptoms of (HPV) is appearing, i took the healing process by contacting Dr uza for natural treatment it works wonders, amazingly ever since I had the herbal treatment i have not feel these horrible disease anymore and my doc told me the virus is gone, i am glad i finally got cured out from this horrible disease. every (HPV) or herpes patients should also get in touch with this herbalist Dr to get ride of these disease forever his email address;druzaherbalcure@gmail.com

    ReplyDelete
  10. I was diagnose with human papilloma virus (HPV) 4 years ago and i met a doctor he told me there is no cure and i have be taking some medication the warts multiplied when trying to removed them and it got me embarrass and pains, luckily few weeks ago i was recommend to Dr bante for natural treatment after one week i got 100% cure and all the wart and pains got disappeared, i sheared this post because its part of my life experience, encase anyone need speedy help about this cure email Dr bante via, bantespelltemple@gmail.com or whatsapp him on +2349063962262. add on hangout bantespelltemple@gmail.com

    ReplyDelete
  11. HOW I GOT MY EX HUSBAND BACK WITH THE HELP OF REAL AND EFFECTIVE SPELL FROM DR Osasu My name is Olivia Jayden, I never thought I will smile again, My husband left me with two kids for one year, All effort to bring him back failed I thought I'm not going to see him again not until I met a lady called Jesse who told me about a spell caster called Dr. Osasu , She gave me his email address and mobile number and I contacted him and he assured me that within 48hours my husband will come back to me, In less than 48hours my husband came back started begging for forgiveness saying it is the devils work, so I'm still surprise till now about this miracle,i couldn't conceive but as soon as the spell was cast,i became pregnant and gave birth to my third child,if you need any assistance from him you can contact him via:email: drosasu25@gmail.com Or WhatsApp or call him now:
    Website http://Drosasu.com.ng +2347064365391 . Dr.Osasu also cures: 1. HIV / AIDS 2. HERPES 1/2 3. CANCER 4. ALS (Lou Gehrig’s disease) 5. Hepatitis B

    ReplyDelete
  12. HOW I GOT MY EX HUSBAND BACK WITH THE HELP OF REAL AND EFFECTIVE SPELL FROM DR Osasu My name is Olivia Jayden, I never thought I will smile again, My husband left me with two kids for one year, All effort to bring him back failed I thought I'm not going to see him again not until I met a lady called Jesse who told me about a spell caster called Dr. Osasu , She gave me his email address and mobile number and I contacted him and he assured me that within 48hours my husband will come back to me, In less than 48hours my husband came back started begging for forgiveness saying it is the devils work, so I'm still surprise till now about this miracle,i couldn't conceive but as soon as the spell was cast,i became pregnant and gave birth to my third child,if you need any assistance from him you can contact him via:email: drosasu25@gmail.com Or WhatsApp or call him now:
    Website http://Drosasu.com.ng +2347064365391 . Dr.Osasu also cures: 1. HIV / AIDS 2. HERPES 1/2 3. CANCER 4. ALS (Lou Gehrig’s disease) 5. Hepatitis B

    ReplyDelete

  13. I am from UNITED STATES i was diagnosed with HIV/AIDS for over 12 years which made loose my job and my relationship with my fiance after he discovered that i was having HIV, he departed from me i tried all my best to make him stays with me, but neglected me until a friend of mine on Facebook from Singapore told me Great healer, who will restore my life back with his powerful healing spell, he sent me the email address to contact and i quickly contacted him, and he said my condition can solved, that he will treat the disease immediately only if i can accept trust him and accept his terms and condition, i Agreed because i was so much in need of help by all means, so i did all he want from me and surprisingly on Sunday last week He sent me a text, that i should hurry up to the hospital for a checkup, which i truly did, i confirm from my doctor that i am now ( HIV NEGATIVE) my eyes filled with tears and joy, crying heavily because truly the disease deprived me of many things from my life, This is a Miracle, Please do not en-devour to email dr.losaherbalhome@gmail.com or whatsapp Dr LOSA on +2349056464736 for healings Thanks
    stay blessed......
    HE ALSO HAVE THIS CURE
    {1}HIV And AIDS
    {2}Diabetes
    {3}Epilepsy
    {4} Blood Cancer
    {5} HPV
    {6} ALS
    {7} Hepatitis B
    {8} COPD (Chronic Obstructive Pulmonary Disease)
    {9} IF YOU NEED YOUR EX LOVER BACK TO LOVE YOU AGAIN.
    https://drlosaherbslhome.wordpress.com

    ReplyDelete
  14. I was diagnose with hpv virus for 5years i broke up with my boyfriend because i contracted the virus from him, luckily i found a herbalist name Dr. onokun everyone testify good of his natural treatment i picked up his address and contacted him. he truly treated me with natural herbs in a week and i got cured. i share this post because ever since i got this treatment I'm perfectly ok with my health. i contacted him through this email.. dronokunherbalcure@gmail.com

    ReplyDelete
  15. LifeVoxel AI - Best Medical Imaging Platform also Provide critical patient-centric delivery of care using intuitive, diagnostic and instantly accessible visualizations over the Internet. 

    RIS PACS
    RIS PACS Software

    ReplyDelete